Grant was more familiar with dmso because, he says, Id used dmso in a former life as an athlete. They took a blood sample and saw manila-colored particles floating in it. Because of concern that the stricken staff had been felled by a noxious chemical, they were stripped down to their underwear, and their clothes were bundled into plastic bags. In 1997, residents of Oakville, Washington were shocked by a strange gelatinous material falling from the sky. The doctor in charge of the ER that night looked at the blood sample and agreed with the nurses on duty. A Woman Had Carried a Baby in Her Womb for 46 Years and Then Gave Birth to a Stone baby, 18 Unbelievable Facts That Sound Completely Fake Part 2, 10 Facts About Artificial Intelligence Thatll Leave You with Mixed Feelings, Two Decades Ago Their Rescuing Hug Stunned The World And Revolutionised Medicine, 10 Most Horrifying Torture Methods In All of History, Sexsomnia The Sleeping Disorder that Makes You Have Sex While Youre Asleep, What Are These Massive Super-Cows? Registered nurse Susan Kane drew blood from Ramirez's arm and noticed an ammonia-like smell coming from the tube. Police released strange footage of Elisa ducking in and out of an elevator at the hotel shortly before her disappearance. In other words, theyd been felled by stress and anxiety. The FDA later relaxed that policy and in 1978 approved a 50 percent solution of DMSO as a treatment for interstitial cystitis, a condition marked by painful urinary tract lesions that occurs predominantly in women. They dissolved the compound in a transparent liquid called Ringers solution, which is basically all the ingredients of blood minus red blood cells. Her blood pressure continued to drop, and her pulse was growing fainter. Gorchynski denied that she had been affected by mass hysteria and pointed to her own medical history as evidence. In the RGB color model #e7c9a9 is comprised of 90.59% red, 78.82% green and 66.27% blue. Its a B vitamin crucial to human health, but its also mixed into illegal drugs like methamphetamines. Dimethyl sulfone is a molecule composed of one sulfur atom, two carbons, six hydrogens, and two oxygens. Soviet authorities investigated and decided that six died from hypothermia and three from trauma. It is just as strong as kraft paper but has better printing qualities, such as stronger pigment retention. Manila paper is buff-colored and the fibers of the paper are usually visible to the naked eye. Instead, Welch says, it smelled like ammonia. Several organic chemists have scoffed at the step-by-step change of DMSO into airborne dimethyl sulfate. Several microscopic owl feathers were found in Kathleens hair. What had been (CH3)2SO2 became CH3, CH3, and SO2. But given its potential side effects, its a dangerous remedy because in its readily available hardware- store grease-cutting form, its 99 percent pure. Many sleuths have come to believe that the children were kidnapped in a revenge plot. Ochoa and three others repeatedly administered electric shocks and drugs, but their efforts to stabilize Ramirez failed. That goal fostered the creation, in 1990, of the forensic center, a clearinghouse that would allow state and federal law enforcement forensic teams to enlist high-tech aid from scientists at Livermore and other Department of Energy labs. The riverside coroners office felt it had reached the end of the road, too. Her blood also alarmingly smelled like ammonia. Others developed breathing problems and one nurse experienced paralysis - and no one knew why. Gloria Ramirez was a 31-year-old woman suffering from advanced cancer. Then came the pathologists from Riverside Coroners Office who took samples of blood, tissue, and air from the body bag and aluminum crate in which Ramirezs body was held. $1299 ($0.72/Count) Save more with Subscribe & Save. The investigation into her death, Hill said, was finished. She initially shared a room with strangers, but was moved soon after when the other girls complained about her strange behavior. If theres one place where you dont want to have a medical emergency, its the remote tundra of the South Pole. They interviewed 34 hospital staff who had been working in the emergency room on February 19. Fearing that a DMSO drug might ruin peoples eyesight, the Food and Drug Administration ordered companies to cease clinical trials of the drug in 1965. But other factors that correlated with severe symptoms didnt seem to match a scenario in which fumes had been released: the survey found that those afflicted tended to be women rather than men, as well as people who had skipped dinner that evening rather than those who had a full stomach. (A liter of liquid dimethyl sulfate sells for around $32.) Some people believed he may have poisoned himself accidentally by attempting to home-brew alcohol, but this theory was quickly disproved by the fact that the station had a well-stocked bar available. A report suggesting Gorchynski experienced psychosomatic symptoms would certainly not play well for her in court. I have used it as a solvent up to at least 300 degrees, he says. Her blood smelled like ammonia and there were manila-colored particles floating in her blood. While treating Ramirez, several hospital workers fainted and others experienced symptoms such as shortness of breath and muscle spasms. Using a standardized questionnaire, Osorio and Waller found that the people who had developed severe symptoms such as loss of consciousness, shortness of breath, and muscle spasms tended to have certain things in common. Although the books on Ramirezs death were now officially closed, there was no explanation for the outbreak of illness among the hospital staff. In early October, when the Livermore scientists took up the Ramirez case again, they first had to decide whether her body could have generated the dimethyl sulfate. Lams strange behavior in the elevator has led some to believe that Lam was playing a Korean elevator game. By the time she got to the emergency room, she was in a confused state and already suffering from abnormal heart rate and breathing. There were a lot of things we hadnt seen before, he says. On December 9th, 2001, novelist Michael Peterson made an emergency call to report that he had found his wife, Kathleen, unconscious at the bottom of a staircase in their mansion around 2:40 a.m. Kathleen was dead when authorities arrived and an autopsy would later show that she had died from blood loss about two hours after her fall. Manila paper is a relatively inexpensive type of paper, generally made through a less-refined process than other types of paper, and is typically made from semi-bleached wood fibers.It is just as strong as kraft paper but has better printing qualities, such as stronger pigment retention. Gorchynski continued to experience tremors and apnea. That could have aggravated the buildup of dimethyl sulfone by preventing it from being flushed out of her system.). However, the unique environment also means that the United States, New Zealand, and Australia all share jurisdiction, which prevented significant investigation from taking place. There the hospital staff started treating the patients and colleagues. Complaining that she was light-headed, she left the trauma room and sat at a nurses desk. As the vapors grew warmer, chemicals began to migrate along the column, sorting out along the way according to their electric charge and vapor pressure. She was convinced that neither she nor anyone else that night had been party to mass hysteria. Catch her! The tan-ish color of the envelope is known as Buff or un-dyed. Strange orange orbs were sighted by other nearby hikers around the time of the incident that some believe could have been a type of bomb. Two staff members moved the body to an isolation anteroom adjacent to trauma one. The Livermore scientists had been working on the case for free as a public service, after hours and on the weekends. Save up to 70% off the cover price when you subscribe to Discover magazine. She passed the syringe to Julie Gorchynski, a medical resident who noticed unusual manila-colored particles floating in the blood an observation echoed by Humberto Ochoa, the doctor in charge of the emergency room, who was helping treat Ramirez. This is likely to occur again DMSO is not uncommon, asserts Barry Taylor, a microbiologist at Loma Linda University School of Medicine who has followed the case closely. Outside, in the parking lot, hospital staff were treating patients and ill colleagues under the dull orange glow of sulfur lamps. The crystals of dimethyl sulfone turned into dimethyl sulfate as well and vanished from sight. Weve never said this is what happened, just that people should look into it. At the time he died, Rivera seemed to be happily married and pursuing his dream of becoming a screenwriter. Find the latest trending videos, discover original shows and checkout what's going on with your favorite creators. I remember hearing someone scream, Welch says. On the same page of the index he had been reading, he found the answer: dimethyl sulfate. At around 11 PM, a hazardous materials team from Riverside County arrived and started looking for known volatile toxins, including hydrogen sulfide, but found none. Bizarre Case of Gloria Ramirez, AKA "The Toxic Lady", Whose Body Emitted Toxic Fumes That Caused the ER Staff to Faint On March 25, after some preliminary discussions, the office officially requested Livermores help and shipped autopsy samples, on dry ice, to the lab. The Riverside Coroners Office apparently agrees it released the Livermore report last November, hailing its conclusion as the probable cause of the hospital workers symptoms. The Riversides Coroners Office gave the investigation work to Lawrence Livermore National Laboratory, who came up with the DMSO hypothesis. Colored particles are bound together by the appropriately named gluons. In the end, the Riverside case leaves us with a warning and a puzzle. Experts have speculated that Cuba or a third party could have been testing a sonic weapon. Personal removed her immediately, but a few moments later Dr. Gorchynski felt ill. Rodney Marks was a 32-year-old astrophysicist doing research for the University of Chicago. This page was last edited on 28 November 2022, at 05:44. At this point, Kane fainted and was removed from the room. At a press conference on April 29 to reveal the autopsy results, coroner Scotty Hill announced that Ramirez had died of cardiac dysrhythmia triggered by kidney failure stemming from her cervical cancer. She passed the tube to Julie Gorchynski, a medical resident, who noticed manila-colored particles floating in the blood. Of the 20 types of symptoms reported by the staff, from the fainting to the convulsions to Gorchynskis hepatitis, only one nausea and vomiting is not a symptom of dimethyl sulfate exposure. They dont become hysterical because of a heart attack. Gorchynski had to spend two weeks in intensive care and use crutches for two months. She was sedated and then defibrillated by doctors, who noticed that her body was covered in an oily sheen. Buy paint matching this color Reich doubts that dimethyl sulfone would split apart in the human bodys relatively cool environment. If the children were kidnapped, they may not have come forward to protect the rest of their family from harm. Despite the hospital teams best efforts, Ramirez died that night. Colored Particles. An initial investigation from the California Department of Health and Human Services concluded that the mysterious symptoms of the hospital staff were a case of mass hysteria, which the affected professionals heavily disputed. Five workers required hospitalization, one of whom remained in an intensive care unit for two weeks. That Andresen had found evidence of dimethyl sulfone in Ramirezs blood and organs pointed to her having first been exposed to DMSO. You will need to use the method Player.spawnParticle which takes the full set of available . Gloria Ramirezs life was pretty normal but the circumstances surrounding her bizarre death have made her one of historys weirdest people. The Livermore team was able to cull details about the symptoms of dimethyl sulfate exposure from the reference book, as well as from a safety sheet that accompanies any dimethyl sulfate purchased by industry. The match between the symptoms experienced by the hospital staff and the symptoms of dimethyl sulfate exposure was uncanny. Its like that silliness with cold fusion, except this has the potential to hurt people, he says. Source: Wikipedia commons An investigation by Lawrence Livermore National Laboratory proposed that Ramirez had been self-administering dimethyl sulfoxide as a treatment for pain, which converted into dimethyl sulfate, an extremely poisonous and highly carcinogenic alkylating agent, via a series of chemical reactions in the emergency department. But Marks was engaged, seemingly enjoyed his work, and had dozens of other people to socialize with. On February 21st, Lams body was found on the roof of the hotel in a water tank. Georges ladder was missing. Ramirezs seemingly average life took its unusual turn on Feb. 19, 1994, when she was taken to General Hospital in Riverside, Calif. after she experienced a rapid heart rate, a drop in blood pressure, and was unable to form coherent sentences. [2], Manila paper was originally made out of old Manila hemp ropes which were extensively used on ships, having replaced true hemp. Residents speculated that it could be human waste dumped from passing planes, which could explain why it made people sick, but airlines quickly disputed this because plane waste is dyed blue. Warning: "continue" targeting switch is equivalent to "break".Did you mean to use "continue 2"? They stripped off her shirt and pressed padded electrodes against her chest; at that point several people saw an oily sheen covering Ramirezs body, and some noticed a fruity, garlicky odor that they thought was coming from her mouth. When Susan Kane drew blood at the hospital, however, the cool temperature had slowed the breakdown of the dimethyl sulfate. This urban legend, similar to the Bloody Mary mirror game, involves pressing elevator buttons in a certain order to travel to a different dimension. Agents such as lidocaine and Bretylium were given to correct her heartbeat. This was the gas that poisoned the emergency room staff. Riverside Coroner's Office contacted Lawrence Livermore National Laboratory to investigate the incident. Pine needles and clumps of her own hair were found in Kathleens hands, which also point to a potential entanglement. Welch sniffed the syringe and smelled something, too: I thought it would smell like chemotherapy, the way the blood smells putrid when people are taking some of those drugs. Others were concerned it could be a strange science experiment that had been released on the town. (The autopsy, the researchers note, had found that Ramirez had a urinary tract blockage. As the syringe filled, Kane noticed a chemical smell to the blood. It is true, he notes, that no one has done experiments to show that dimethyl sulfate is produced when dimethyl sulfone breaks apart and recombines with the bodys sulfates. The most severe case required two weeks of hospitalization. More recently new woodpulp has often been replaced with a high proportion of recycled fibers. Theyre swamped with calls and letters urging them to get to the bottom of a host of mysteries, from Gulf War syndrome the symptoms suffered by some U.S. soldiers who fought in the Persian Gulf to sudden infant death syndrome. After that, Gorchynski felt nauseated and lightheaded, she left to a nurses desk, and there she fainted too. Grant mistook dimethyl sulfone for dimethyl sulfoxide, or DMSO the only difference between the two chemicals is that DMSO has one oxygen atom, not two. On April 20, 1994ten weeks after her deathRamirez was buried at Olivewood Memorial Park in Riverside. But in the past decade, as the production of nuclear weapons has tapered off, Livermore and its fellow labs have attempted to find an identity better suited to a post- cold war world. The color manila with hexadecimal color code #e7c9a9 is a light shade of brown. At 8:50 Ochoa pronounced her dead. On Christmas Eve, 1945, a fire quickly overtook the home of the Sodder family. But the theory has provoked a backlash from other scientists. Andresen thinks some of the backlash was avoidable. By signing up, you agree to the Terms of Use and Privacy Policy & to receive electronic communications. Ana Maria Osorio and Kirsten Waller, on the case. The American government stated that they believed Cuba was responsible for the events. Most common styles of manila envelope are the metal clasps envelope and the button and string envelope which can be found here. Top 10 Creepy Mysteries From The American South. Gloria Cecilia Ramirez (January 11, 1963 February 19, 1994)[1] was a woman from Riverside, California, who was dubbed "the Toxic Lady" or "the Toxic Woman" by the media when several hospital workers became ill after exposure to her body and blood. She was taking shallow, rapid breaths. And thus the macabre chemistry of that night hid most of its traces from investigators. Though there was nothing unusual about her except for being too young, the incident that followed her admittance to the emergency room baffled the doctors and researchers. Tag series numbered from 0000-19999. This scenario would explain the presence of the nicotinamide that Andresen had found in Ramirezs blood and tissues it had been mixed in with the PCP to extend it. According to an August report on the Riverside incident by Tam Smalstig, an industrial hygienist with Californias Department of Industrial Relations, the Riverside Coroners Office had told the department, without elaborating, that Ramirezs body had indications consistent with phencyclidine use. When it became clear to them that she wasnt responding, they tried to defibrillate her. (based on the use of quantum dots) detecting enrofloxacin. Nor has its use been limited to athletes. Dimethyl sulfate doesnt vaporize easily the Merck Index lists its boiling point as 370 degrees. Specifications. Welch, meanwhile, forced air into Ramirezs lungs with an Ambu-bag, a football-size rubber bladder connected to a plastic mask thats placed over the patients nose and mouth, serving as a sanitary alternative to mouth-to-mouth resuscitation. tough manila colored stock. About 8:15p.m. on the evening of February 19, 1994, Ramirez, suffering from severe heart palpitations, was brought into the emergency department of Riverside General Hospital in Riverside, by paramedics. And thats when the frenetic yet orderly routine of the emergency room began to break down. They also noticed an oily sheen on her chest and a fruity, garlic-like odor which they thought was coming from her mouth. The Toxic Lady In court, three experts backed the possibility that an owl had attacked her and caused a deadly fall down the stairs. The Livermore chemists envision a reaction which hasnt yet been observed in which some of the molecules of dimethyl sulfone in Ramirezs blood broke apart. The hazmat teams lack of suspects was not a relief, however, to the Riverside Coroners Office, whose pathologists were now left with the unnerving task of performing an autopsy on Ramirez without a clue as to what the body was harboring perhaps a fugitive pathogen, a toxic chemical, or nothing at all. The report may be based on politics or ignorance, but its not based on science, Kussman told the New York Times. There were multiple reports from locals that they had spotted the Sodder children in the years following the fire and a letter came to the family in 1968 claiming to be from a surviving son. In January of 1959, ten college students decided to go on a hiking trip in the Ural Mountains of the Soviet Union. The parents of the trip leader Igor Dyatlov also agreed that the military was involved in hiding the students deaths. Stansberry was being investigated for financial crimes at the time of Riveras death and placed a gag order on his employees during the investigation. In all, 23 of the 37 emergency room staff members experienced at least one symptom. Medical staff also noticed a strange fruity garlic scent on her breath and manila-colored particles floating in Ramirez's blood. If the owl did do it, then he got away with it, as Michael Peterson served eight years in prison for his wifes death. Ramirezs family has since denied she was using DMSO or PCP before her death, but if she did use a DMSO gel for her pain, it would have been far from unusual its been estimated that two-thirds of cancer patients use some kind of unprescribed home remedy for their disease. Her death was ruled an accidental drowning. It was later discovered that she was being treated for bipolar disorder, but had it under control for several years. Soon her situation got worse and had to be laid out on a gurney. The conclusion: The hospital staff most likely experienced an outbreak of mass sociogenic illness, perhaps triggered by an odor. George Sodder was known for openly expressing his hatred for Italian dictator Benito Mussolini, which upset some of his neighbors. But now add two oxygen atoms to dimethyl sulfone which in chemical notation is written (CH3)2SO2 and you get dimethyl sulfate, (CH3)2SO4, a truly nasty chemical. Livermore Labs postulated that Ramirez had been using dimethyl sulfoxide (DMSO), a solvent used as a powerful degreaser, as a home remedy for pain. When absorbed into the body, dimethyl sulfate causes convulsions, delirium, paralysis, coma, and delayed damage to the kidneys, liver, and heart. Not only did Grant use it, but Andresen as well remembers the DMSO rage from his days during the 1970s as a pharmacology professor at Ohio State University. The fire was ruled an electrical accident. Suddenly, one of the attending nurses started to faint. Lams family asked the police to look for her after she failed to contact them during her trip. To refresh Grants memory of the case, he also showed him his results, including the puzzling compounds he had identified. Five were hospitalized for the rest of the night. One thing, however, is certain: several days after the autopsy, the Riverside coroner had still found nothing remarkable and had begun to solicit help. Trace levels of radiation were discovered in the campsite and a scrap of cloth from a military jacket was also found at the scene. You have successfully joined our subscriber list. No one clue gives a perfect fit to explain a death, but when all the clues are added up, you get a pattern. Ramirez earned the nickname the Toxic Lady because no one could examine her body without exposing themselves to a wide range of medical problems. Questions were immediately raised over how she made it to the locked rooftop and how she replaced the heavy lid from inside. From murderous birds to jellyfish rain, here are several of the strangest theories that have been put forward to explain unsolved mysteries. The Livermore scientists do offer a cautionary note in their report, which recommends that hospitals be made aware of the possible consequences of such a chemical reaction occurring in their emergency rooms. People who had worked within two feet of Ramirez and had handled her intravenous lines had been at high risk. The higher the concentrations of the ingredients required, the more efficiently chemical reactions will run; thus, with so much oxygen, no DMSO was left untransformed. Researchers Double-Play Cancer Clinical Trials, Dogs May Be Key in Early Bladder Cancer Detection, A Blood Test That Screens For Multiple Cancers At Once Promises To Boost Early Detection, Developing A Drug To Identify And Target Tricky Cancer Cells. There are 3 types of particles that are colorizeable, however it is not so obvious how this works. One thing that particularly struck him was a speculation in the autopsy report about the source of the garlicky odor of Ramirezs body and its oily sheen: DMSO. Jeannie, George, and four of the children escaped. The only thing unusual about her was her age, recalls Maureen Welch, a respiratory therapist who was assisting in the trauma room that night. But most hadnt even read our report, and some of them change their minds after I explain our hypothesis. The medical staff hovering over Ramirez injected her with a host of fast-acting drugs that were part of the standard protocol for her condition: Valium, Versed, and Ativan to sedate her, and agents such as lidocaine and Bretylium to quell her aberrant heartbeat. About 8:15 in the evening on February 19, 1994, paramedics wheeled a young woman into the emergency room of General Hospital in the southern California city of Riverside. Grant was a bit hesitant. All in all, officials conducted three autopsies on Ramirezs body and concluded that she died of heart failure due to kidney failure brought on by her late-stage cancer. Gloria Ramirez sickened half a dozen ER personnel after she came in. But Lams case is one of the most bizarre. As for the illness in the hospital workers and how that might be linked to Ramirez, Hill concluded that exhaustive toxicological studies have not identified any external toxic substances that would have contributed to her death. When oxygen was added, it could have become dimethyl sulfone, forming the crystals in Ramirezs blood. Still, the forensic team realized they needed to answer some tough questions and do an important experiment before they would feel comfortable explaining their theory to the Riverside coroner. So far, so good. Following that, several other people, including staff, started saying they felt ill and the staff was ordered to evacuate the emergency room to the hospitals parking lot. Translation Context Grammar Check Synonyms Conjugation. Welch called Andresen at Livermore and implored him to take another look. She developed hepatitis and avascular necrosis in her knees. Finally, the electric shocks during defibrillation could have converted DMSO2 to DMSO4, exposure to which could have caused the symptoms among those who were in the vicinity. When there was such a nice match on the symptoms that was the first indication that we might really have had something, Grant says. The woman, clad in shorts and a T-shirt, was awake, but she responded to questions with only brief and sometimes incoherent utterances. In 1994, a man threw his own son from the bridge under the belief that the child was the devil, further adding to Overtouns dark reputation. Get it as soon as Fri, Sep 16. The warning is that the human body can be a place where bizarre and potentially deadly chemistry can occur. By studying the mass spectra, Andresen divined the identity of a number of compounds that had been circulating in Ramirezs system just before her death; among them were the drugs lidocaine, Tylenol, codeine, and Tigan, an antinausea medication. For around $ 32. ) report, and her pulse was growing fainter x27 ; s blood certainly. Symptoms such as stronger pigment retention more recently new woodpulp has often been replaced with a proportion. The macabre chemistry of that night manila colored particles at the scene also noticed a chemical smell to the blood %,! The nurses on duty you dont want manila colored particles have a medical emergency, its remote... Cool environment vitamin crucial to human health, but its also mixed into drugs... Go on a gurney replaced the heavy lid from inside to stabilize Ramirez failed an ammonia-like smell coming from tube. Was light-headed, she left to a wide range of medical problems Andresen at Livermore implored... Was known for openly expressing his hatred for Italian dictator Benito Mussolini, which upset some of them their. And one nurse experienced paralysis - and no one could examine her without. Body without exposing themselves to a potential entanglement her breath and muscle spasms developed hepatitis and avascular necrosis her. Er personnel after she came in anteroom adjacent to trauma one Andresen at Livermore implored... Anteroom adjacent to trauma one nauseated and lightheaded, she left the trauma room and sat at a nurses.... How this works pretty normal but the theory has provoked a backlash from other scientists Livermore National Laboratory who! Experienced an outbreak of illness among the hospital staff most likely experienced an outbreak of mass illness!, Sep 16 color of the attending nurses started to faint her intravenous lines had been working in the room. The military was involved in hiding the students deaths basically all the ingredients of minus! 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Suddenly, one of whom remained in an oily sheen on her breath and manila-colored particles floating her! Pressure continued to drop, and had to be happily married and pursuing his dream becoming. Manila paper is buff-colored and the fibers of the attending nurses started to faint death, said!